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Stories 1 - 10 for Phosphorylation

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Researchers identify proteins in lung cancer cells that may provide potential ...

Webnewswire.com - ‎17 hours ago‎
Signal transduction is in large part controlled by a process called phosphorylation. When a protein is phosphorylated it either becomes active or repressed ...

Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal ...

7thSpace Interactive (press release) - ‎Nov 27, 2009‎
... as well as down-regulated Raf phosphorylation at Tyr(340/341) site, and its down-stream signaling molecules ERK and CREB expression followed by 24 h and ...

Insulin signaling pathways in a patient with insulin resistance of difficult ...

7thSpace Interactive (press release) - ‎Nov 27, 2009‎
However, when IRS-1 protein content associated to membrane and IR tyrosine phosphorylation were analyzed, no IR activity was observed, ...

Estrogen Receptor Activation Predicts Tamoxifen Response

MedPage Today - Crystal Phend - ‎Nov 27, 2009‎
Preclinical studies had shown that phosphorylation of ER-alpha at a location known as serine-118 (ER-alpha S118-P) is required for the receptor to be ...

Ser62 – Another piece of the puzzle…

ScienceBlog.com (blog) - ‎Nov 27, 2009‎
One of the ways in which this is achievable is by characterising the phosphorylation sites of a protein ie FLCN and identifying which kinases are ...

The role of mutations in core protein of hepatitis B virus in liver fibrosis

7thSpace Interactive (press release) - ‎Nov 26, 2009‎
Mutations in CTL epitopes and in phosphorylation sites of C-terminal domain of core protein also were associated with higher liver fibrosis (P= 0.003 and P= ...

Estrogen Receptor-Alpha, Breast Cancer Patients and Tamoxifen Response

Science Daily (press release) - ‎Nov 26, 2009‎
... tamoxifen among patients whose estrogen receptor (ER)-positive tumors had high levels of phosphorylation of ER-alpha; at serine-118 (ER-alpha S118-P), ...

Crosstalk Between Critical Cell-Signaling Pathways Holds Clues to Tumor ...

Science Daily (press release) - ‎Nov 25, 2009‎
The investigators noted that this cascade culminates in the phosphorylation of alpha-catenin and ultimately promotes beta-catenin activation in the nucleus ...

PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer ...

7thSpace Interactive (press release) - ‎Nov 25, 2009‎
In our previous study, we observed that PRL-3 could decrease tyrosine phosphorylation of integrin beta1 and enhance activation of ERK1/2 in HEK293 cells. ...

Severe stress could result in epigenetic marks on hippocampus

HealthJockey.com - ‎Nov 25, 2009‎
... that the epigenetic changes such as the methyl marks others like acetylation and phosphorylation, could play an important function in the brain's ...
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