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Stories 1 - 10 for Ligand

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Mammalian System for Controlling Bone Remodelling Also Regulates Fever

Science Daily (press release) - ‎9 hours ago‎
The so-called RANK protein and the molecule that binds to it, the RANK ligand or RANKL, form a focus of the work of Josef Penninger, director of the ...

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Science Magazine (subscription) - Richard O. Hynes - ‎12 hours ago‎
The activated TGF-β is not released in soluble, diffusible form but appears to act only at short range, perhaps as a bound solid-phase ligand. ...

Fas and fasl gene polymorphisms are not associated with cervical cancer but ...

7thSpace Interactive (press release) - ‎17 hours ago‎
Polymorphisms in the Fas (fasr) and Fas ligand (fasl) genes have been reported to be associated with cervical cancer in certain populations. ...

Financing Drug Discovery: Recent Deals

Seeking Alpha (blog) - Marie Daghlian - ‎Nov 26, 2009‎
... where structural insight is anticipated to elucidate receptor-ligand interactions and deliver both best- and first-in-class GPCR therapeutic candidates. ...

Amgen Recognized for Best Pipeline and Best New Drug at Scrip Awards

PR-CANADA.net (press release) - ‎Nov 25, 2009‎
Denosumab is the first fully human monoclonal antibody in late stage clinical development that specifically targets RANK Ligand, an essential regulator of ...

PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth ...

BMC Pediatrics - ‎Nov 25, 2009‎
c-Met is a tyrosine kinase receptor for hepatocyte growth factor/scatter factor (HGF/SF), and both c-Met and its ligand are expressed in a variety of ...

Ca 2+ Puffs Originate from Preestablished Stable Clusters of Inositol ...

Science Magazine (blog) - ‎Nov 25, 2009‎
These ligand-gated ion channels liberate Ca 2+ to generate local signals known as Ca 2+ puffs. We tested the hypothesis that IP 3 itself elicits rapid ...

New Method of Fighting A-H1N1 in the Works

Softpedia - Tudor Vieru - ‎Nov 24, 2009‎
This is one of the main reasons why the LEAPS (Ligand Epitope Antigen Presentation System) was created at the Vienna, VA-based company Cel-Sci. ...

Oxagen Raises $26M to Boost Midstage Asthma Compound

BioWorld Online - Nuala Moran - ‎Nov 24, 2009‎
That was before prostaglandin was shown to be the ligand for CRTH2, and thus that blocking the effects of CRTH2 prevents the release of ...

Molecule Makes Obese People Develop Diabetes

RedOrbit - ‎Nov 24, 2009‎
... Vidal-Puig A., Zorzano A., Langin D. y Fajas L. "CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance". ...
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